Lukas Muttenthaler

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Senior Machine Learning Research Scientist at Aignostics and former part-time postdoctoral researcher in the Explainable Machine Learning Group at Helmholtz Munich & TU Munich, working on representation learning and post-training for computer vision foundation models.

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Research Profile

I am a (full-time) Senior Machine Learning Research Scientist at Aignostics and a (part-time) postdoctoral researcher in the Explainable Machine Learning Group at Helmholtz Munich & TU Munich. At Aignostics, I introduced and lead the post-training research agenda for the company's vision foundation models, spanning self-supervised learning, vision–language alignment, and multi-task learning for computational pathology. Prior to that, I was a Student Researcher at Google DeepMind and a PhD student in Machine Learning at TU Berlin and the Berlin Institute for the Foundations of Learning and Data (BIFOLD). Throughout most of my PhD I have also been a guest researcher in the ViCCo Group at the Max Planck Institute for Human Cognitive and Brain Sciences. I was mainly advised by Klaus-Robert Müller (TU Berlin) and co-supervised by Martin Hebart (MPI), Simon Kornblith (Anthropic), and Andrew Lampinen (Google DeepMind). During my PhD, I've been part of a one-year Research Collaboration between TU Berlin and Google Brain, where I was advised by Simon Kornblith. Previously, I was a MSc student in IT & Cognition / Computer Science of Isabelle Augenstein and Johannes Bjerva at the University of Copenhagen where I mostly worked on Question Answering and Machine Translation.

My research mainly revolves around representation learning in computer vision. In particular, I try to understand the factors that influence the degree of alignment between human mental and neural network representations and use inspiration from human cognition to improve deep learning models. My goal is to build interpretable (vision) foundation models that generalize to downstream out-of-distribution settings (similar to how the human brain does); something that we partly achieved in this Nature paper. More recently, I have been working on foundation models for medical imaging—specifically computational pathology—where I have gained deep expertise in histopathological image analysis, foundation model post-training, and multi-task learning for H&E- and IHC-stained tissue. Beyond raw performance, I am deeply invested in questions of AI safety and alignment—a natural extension of my work on representational alignment between humans and neural networks, where understanding and controlling the internal representations of AI systems is key to building models that are interpretable, trustworthy, and aligned with human values.

Occasionally I dabble in philosophical discussions about representational alignment and try to develop common language across research disciplines together with other people in the field. Recently, I've been thinking a lot about the transferability of representational similarities across datasets. Have a look at my Google Scholar for more information about my work. Feel free to reach out to me, if you believe our research intentions are aligned (pun intended) and you are keen to collaborate on a project.

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